Abstract: In the process of the comprehensive deepening and promoting the railway safety management standardization, this article focused on the core problem that management was the main risk sources of railway safety, standardized the cadre accountability process management as a breakthrough, combined the cadre responsibility with the security risk management, the implementation of the priorities, work standards and etc., developed and applied the cadre responsibility management information system. It was implemented “work in a plan way, traces for assumed responsibility, evaluation with basis, management with accountability” for the railway cadres at all levels, provided necessary technical support to standardize railway cadres responsibility management, strengthen risk management, implement the safety management standardization.