Abstract: The electronic bill of railway freight transportation is the core requirement to implement railway freight paperless office, improve the quality of customer service and transportation organization efficiency. This paper analyzed the present situation of freight paper bills transfer and the construction of the relevant system, studied on the feasibility of the electronic bill of railway freight transportation, combined with the informatization overall planning requirements of China Railway, proposed the electronic bill management system for the railway freight transportation, the system architecture, logical architecture, technical architecture and data processing strategy. It has a certain reference for the research and development of electronic bill of railway freight transportation.