Abstract: To improve the efficiency and accuracy of interlocking table compilation, this paper designed an automatic generation software for interlocking table based on custom entity. The paper used the AutoCAD secondary development interface to read the data information of customized entities of signal equipment created using Object ARX, automatically generated the station type data structure based on the structural characteristics of the signal equipment layout plan, used Deep First Search (DFS) algorithm to search for routes, and according to the principles of interlocking table compilation, processed route data and generated interlocking data. The on-site trial results show that the software can interact with the signal equipment layout plan in real-time and quickly access the AutoCAD database, directly call the entities in it, generate standard format railway station interlocking tables and subway vehicle interlocking tables with an accuracy rate of over 99% and high universality.