Abstract: To ensure the safe and stable operation of the informatization infrastructure environment and platform has become an important task in the daily work of the whole railway.At present, many railway informatization infrastructure environments and platforms have the conditions of internal and local high safety and effective operation and maintenance. However, in the face of special needs such as remote operation and maintenance and external multiparty cooperation operation and maintenance that may be involved, how to continue to ensure the safety, timeliness and effectiveness of operation, and to realize the manageability, controllability and traceability of its behavior still needs constant thinking and serious research.In view of the above actual situation in the work scene, combined with the author's many years of practical experience and technical accumulation, this article carried out technical analysis and thinking from the perspective of secure transmission authentication, cloud desktop and EMM, summed up three kinds of remote service security guarantee modes, and gave corresponding suggestions and opinions on how to use various resources to assist the safe and stable operation and maintenance of informatization.