Abstract: The application of BIM (Building Information Modeling) technology in the mechanical and electrical engineering of Nanyang East Railway Station included the establishment of three-dimensional family library model for the mechanical and electrical equipment in the station building, the arrangement of the pipelines in each speciality, the collision inspection, the optimization of the collision pipelines, and the implementation of the optimal layout of the pipelines.Field verification shows that BIM Technology can make reasonable arrangement for the construction organization on site, control the construction progress and quality directly, reduce the occurrence of rework and return to work, save cost and construction period,implement the visual and refined management and control of all parties involved in the project, and provide guarantee for the completion of Nanyang East Railway Station project on schedule and with high quality.