Abstract: The mode of "information system + management method" was adopted in the material and equipment management information system of railway engineering construction to study the information-based supervision problems of all participating units in the construction of railway in terms of material supply progress, material supply quality, onsite acceptance, material use tracing, etc. This article implemented the intelligent early warning of plan submission and material supply through big data intelligent algorithm, and strengthen the quality management of on-site material acceptance and inspection by applying mobile handheld terminal, GPS positioning technology and image data file upload function.The system has been put into operation and the results show that the application of big data, mobile office, GPS positioning technology and other information means in the material and equipment management information system can improve the rationality and accuracy of planning, reduce the management difficulty of the construction site, effectively supervise the presence of site personnel, and improve the acceptance quality of materials.