Abstract: By using the resources of the safety big data application platform of Beijing Railway Administration and big data analysis technology, a research is made on the design of railway safety comprehensive management system of Railway Administration. Via data mining and analysis, this system can help safety management personnels reveal the characteristics and regularity of various hazards such as accidents, faults and safety problems from different perspectives, probe the correlations and evolution of various hazards and safety events, and discover the trends of safety accidents and faults, thus offering a new decision support tool for railway safety supervision and management.