Abstract: This paper introduced the concept and key technology of blockchain, analyzed the requirements of data exchange and data sharing in railway logistics multimodal transport and international intermodal transport, and combined with the current situation of railway freight information system, researched on the construction of multiparty cooperation platform of railway logistics blockchain. The paper also analyzed the application scenarios of intermodal transport, whole-process logistics tracking, logistics credit reporting and finance, and railway freight safety and security. It will provide a reference for the further research of blockchain in railway freight multimodal transport in the future.