Abstract: With the rapid development of urban rail transit network, the number of train transfer points between lines is increasing. The coordination of train transfer station schedules directly affects the service level. It is necessary to coordinate the arrival and departure time of transfer station trains according to the characteristics of passenger flow distribution in the network, so as to minimize the waiting time of passengers at transfer stations and improve passenger travel efficiency. This article took the train connection time point between lines as the optimization object, took the transfer and connection demand of key transfer stations as the leading factor, established the optimization model of transfer and connection scheme arrangement, and implemented the optimization of transfer and connection time based on the dynamic optimization of the overall transfer waiting time of the network at the network level. Taking Guangzhou Metro Line Network as an example, the article used the model development software to get the optimal time points of transfer and connection which met the needs of the site, and provided technical support for the collaborative compilation of train operation plan under the condition of network operation.