Abstract: The implementation of a large number of Railway Information Systems has brought convenience at work. However, it also created the problems of high maintaining cost of old servers and low utilization rate of new servers. This article combined with the present situation of Information System application in Harbin Railway Administration, took the integration process of the servers and Information System as an example, used the VMware virtual cluster technology to design the integration process from multiple perspectives, summarized some experiences and some matters needing attention in the implementation process. The author hoped that this article could provide some useful help for the colleagues.