Abstract: Aiming at the problems of irregular documents, complicated approval process and relying on manual information transmission in the current cost reimbursement management in railway enterprises, this paper designed and developed an expense reimbursement management system for railway enterprises. In the process of implementation, the key technologies such as front-end and back-end separation, distributed deployment, configurable form process and automatic generation of accounting vouchers were adopted to implement the standardization of expense reimbursement documents, electronic approval process and automation of information transmission. The practice of the system in railway enterprises shows that it greatly improves the efficiency of business examination and approval and accounting, and improves the efficiency of employee expense reimbursement by nearly 50%, standardizes the financial reimbursement management of railway enterprises and has a strong application value for other railway enterprises.