Abstract: In order to improve the safety guarantee ability of railway transportation and implement the precise safety management and control of equipment and personnel, this article designed the overall application scheme of safety big data technology of railway administration to implement the business functions of safety risk analysis, safety hazard analysis, accident failure analysis, equipment profile analysis, personnel profile analysis, comprehensive safety assessment, comprehensive safety management, etc.This scheme has certain promotion and application value for mastering the safety situation of railway administration, finding the weak links of safety and guiding the safety supervision and inspection.