Abstract: To enhance the market competitiveness of high-speed railway in the increasingly competitive transportation market, it was urgent to formulate a high-speed railway fare strategy adapted to the comprehensive market environment. Therefore, this paper proposed a high-speed railway ceiling-price adjustment algorithm under the comprehensive market environment, and incorporated cost and economic level factors into the quantitative adjustment system of ceiling-prices simultaneously. It clarified the mechanism of economic level influencing ceiling-prices, and adopted principal component analysis, multiple regression and cost-plus pricing methods to explore the quantitative relationship between ceiling-price related indicators (including passenger flow, transport capacity, operating cost and passenger affordability) and major economic level indicators. On this basis, the paper calculated the market-oriented ceiling-prices of high-speed railway lines, and carried out verification experiments based on historical data. Experimental results show that the proposed algorithm has favorable feasibility and effectiveness.