Abstract: To ensure the safe evacuation of passenger flow in emergency situations at metro stations, this paper carried out research on the modeling and application of passenger flow evacuation in metro stations under the influence of multiple factors. The paper adopted the Legion simulation platform to construct a passenger flow evacuation model for metro stations under the combined influence of multiple factors, evaluated the overall congestion status of the station, analyzed the evacuation time of the station’s main facilities, and compared the results with the evacuation time specified in the relevant standards to support the formulation of operation and organization plans. Taking Yushan Road Station on Nanjing Metro Line 10 as an example, the paper simulated the peak-hour passenger flow evacuation scenarios for future operations. The simulation results show that in emergency events, the evacuation time of the platform, concourse, and Yushan Tianjie passage of Yushan Road Station all meets the regulatory requirements. This not only ensures the safety of station evacuation, but also provides a theoretical basis and reference for subsequent evacuation simulations of stations with similar influencing factors.