Abstract: In order to solve the problems of low efficiency, manual image omission, and poor passenger experience in the security inspection of Nanchang Railway Station of China Railway Nanchang Group Co. Ltd., this paper designed an intelligent security inspection system for Nanchang Railway Station. Nanchang Railway Station is under the jurisdiction of Nanchang Station, Nanchang West Station, and Nanchang East Station. The paper set up dispatching servers and image analysis servers in the information room of Nanchang Station, and connected the security screening instruments, disposal platforms, and cameras of each security screening channel to the safety production network, utilized key technologies such as centralized analysis of prohibited and restricted items, centralized image judgment in security inspection, disposal of prohibited and restricted items based on package image association, and automatic sorting of packages to implement security inspection operations and management functions. The pilot project has shown that the system has improved the quality, efficiency, management level, and passenger experience of security inspection at Nanchang Railway Station, and can provide reference for improving the quality of security inspection at other passenger transport stations.