Abstract: The Large-scale track maintenance machinery operation collision avoidance system is a set of operation safety protection equipment, which assists operators to read the location between vehicles and carry out automatic collision warning. The system implements vehicle location and distance judgment by means of GPS positioning, laser ranging and wheel diameter pulse counting, realizes vehicle communication through radio station and 4G network module. The real-time monitoring of the distance between vehicles and the current vehicle speed are processed by collision avoidance model algorithm, and the collision warning information of vehicles is obtained to realize the anticollision warning function of large track maintenance machinery vehicles. In the field test, the system can carry out vehicle collision warning in advance of more than 1 minute ahead of schedule at 60 km/h speed, effectively guarantees the safety of large-scale track maintenance machinery.