Abstract: In recent years, with the rapid development of railway construction, the railway comprehensive transportation hub based on railway passenger station has become an important part of the large-scale comprehensive transportation hubs in China. The development of big data, artificial intelligence and other new technologies has provided favorable conditions for the optimization of railway comprehensive transportation hubs, and the research on intelligent systems of railway comprehensive transportation hubs has become a general trend. Aiming at the existing problems and based on various business needs and development requirements of railway comprehensive transportation hubs, this paper clarifies the construction objectives of intelligent systems of railway comprehensive transportation hubs, proposes the overall framework, support systems and application framework, which can provide reference for the construction of intelligent systems of railway comprehensive transportation hubs..