Abstract: Aiming at the current problems of decentralized customer management of advance payment for railway freight, low efficiency in the use of advance payment for customers, non-standard operation and use process of advance payment, and heavy workload of manual entry of vouchers, the centralized accounting management information system of advance payment for railway freight is designed and implemented. Based on the analysis of business requirements, the design scheme of the system is proposed, which adopts the overall architecture of centralized deployment and multi-level applications and the cloud computing resources of the main data center of CHINA RAILWAY are used to build the operating environment of the system. This paper describes the composition, operating environment configuration, operation monitoring, logical architecture, main functions, and data interfaces of the system. The system realizes unified management of freight advance payment and centralized accounting of advance payment data by the railway administration, in which advance payment for railway freight can be deposited at one point and settled at multiple points to improve the utilization rate of customers' funds. Through the realization of data exchange and sharing with other related systems, related vouchers, accounts and statements can be automatically generated and transmitted, thus reducing the workload of business personnel and helping to improve data quality and standardize the business process.