Abstract: Starting from the current situation of disaster recovery construction of railway information systems, this paper focused the research on the key technologies of disaster recovery based on the infrastructure cloud of Railway Master Data Center and the construction demand of Disaster Recovery Center, mainly including data replication, active-active scheme and local/remote disaster recovery, business handover and self-healing, cloud disaster recovery service. Besides, the safeguard level of disaster recovery for railway application systems were graded and corresponding disaster recovery schemes of different information systems were recommended based on railway cloud. The research results can provide a reference for the construction of railway disaster recovery center and the selection of disaster recovery architecture for application systems and lay a research basis for the development of disaster recovery service of railway cloud.