Abstract: As the passenger stations are key places for railway passenger transport organization, any emergency occurring in the passenger stations will bring adverse social impacts. In the face of emergencies, how to ensure that the existing resource conditions and response mechanism of the passenger station can effectively control the evolution of the situation is one of the urgent problems to be solved. Through analyzing the basic work flow of emergency response operations of the railway passenger station, the simulation requirements of emergency response before, during and after the emergency response are clarified. Then, the digital twins emergency response model of passenger station is established based on the concept and method of digital twins and the main functions of the emergency response simulation software for passenger station are designed. Furthermore, the simulation functions of typical scenarios, many trains delay, large passenger flow, fire and violence, are refined, thus laying a foundation for the further development of the emergency response simulation and capacity assessment application of passenger station.