Abstract: In the development process of computer interlocking simulation system for urban rail transit, the design process is easily affected by the size and complexity of the specific station yard. To solve this problem and increase the universality of the design of computer interlocking simulation system, make it standardized, the design and development of a set of urban rail computer interlocking simulation platform with universal reference significance was put forward by using the data storage environment provided in the SQL database and the object-oriented C# programming language, and matching the mouse coordinates with the device coordinates. The database was compiled according to the line information, the interface was drawn by using line equipment static data, the acquisition drive simulation system and communication system were designed. Finally, the design and development of the whole interlocking simulation platform was implemented. In the laboratory, taking the basic approach as an example, the experimental results show that the system can correctly and reliably implement the computer interlocking function.The test results verify that the universal design plan of the system is feasible, and meets the design requirements of the system, which provides a new idea for the development of computer interlocking simulation system for urban rail transit in the future.