Abstract: Transport enterprises demand for railway transportation information is increasing. Starting from the actual needs, this paper proposed a railway transportation information exchange plan based on MQ middleware. The MQ, Oracle database technology, network security platform technology, data encryption and decryption technology were used to standardize the railway transportation information exchange and information service interface. The paper also introduced the overall architecture, physical structure, and data service, established the construction target and content. A self-owned railway vehicle enterprise was taken as an example to give details of the data transmission process. It was implemented the standardized, safety and efficient transmission of railway transportation information among enterprises, reduced the logistics cost of enterprises and increased economic benefits.