Abstract: This paper researched on the public transit operation scheme for intercity high-speed railway network of Hu(Shanghai)—Ning(Nanjing)—Hang(Hangzhou). It was determined the train routing and stop pattern, set the priority of each line from the highest to the lowest successively as Hu-Ning Line, Hu-Hang Line, Ning-Hang Line. By regarding Hu-Ning Line with the highest priority as the benchmark, the operation mode was to set the same interval for each line within the whole network during the rush hour. The train marshalling and operation interval were taken as the main decision variables to build the optimization model of operation scheme. The optimization objective of the model was to minimize the sum of the square deviations between the section passenger flow and the standard train capacity, and minimize the number of the train stocks. By using the fuzzy optimization algorithm for multi-objective planning and running the software lingo, the public transit operation scheme for intercity high-speed railway network of Hu—Ning—Hang was achieved.