Abstract: Because of the strict requirement on track fegularity of high-speed railway, the construction of the adjacent building has an inevitable influence on the high-speed railway operation. Taking an intercity railway construction located parallel to the high-speed railway as the study background, a numerical model using software of ABAQUS for large finite element analysis with related parameters setting was established to simulate construction process and analyze the deformation response and axial force effect of existing railway bridge pile foundation. The results could be used to define and implement preventive actions to mitigate identified risks and insure operation safety. This article could provide reference for numerical simulation and construction of similar engineering.