Abstract: This paper introduced the application project of Cloud Computing in the railway information based infrastructure integration and construction, described the necessity of Cloud Computing in railway field, analyzed the main problems which were existed in the infrastructure of railway corporation level and railway administration level, also analyzed the requirement to Cloud Computing.According to the obtained requirements, the goal of applying cloud computing in China's railway and the corresponding mainframe, together with key technologies, were also given to improve the efficiency on the hardware and the software, provide the basis of the information systems and enhancing the economy performance.