Abstract: In response to the problems of mismatched design information, chaotic interface relationships, and poor readability in traditional high-speed railway system design using textual design methods, this paper proposed an integration method of high-speed railway system based on Model-Based Systems Engineering (MBSE). With the system engineering concept as the core, the paper implemented the transformation of design methods from "text-based" to "model-based", and took the design of high-speed railway passenger transportation scenarios as an example, conducted applicability analysis by constructing a system architecture model. The results show that this method can be used for requirement analysis, system architecture design, interface relationship description, and indicator parameter calculation of high-speed railway system. The established architecture model intuitively displays various design information of complex high-speed railway systems. At the same time, due to the uniqueness and correlation of the architecture model and interfaces, this method achieves traceability of the design process, provides support for the integration and forward design of high-speed railway systems.