Abstract: This paper studied the intelligent supervision system for railway enterprises based on knowledge graph, which solved the problems of non-standard, difficult, and technologically backward supervision work in railway enterprises. The paper designed an intelligent supervision system architecture, constructed a knowledge graph of supervision tasks and a cloud graph of intelligent supervision knowledge, implemented functions such as intelligent retrieval, intelligent planning, and decision-making assistance for supervision tasks. The application results in railway related enterprises indicate that the system can effectively improve the quality and efficiency of supervision work, providing decision-making support for management personnel at all levels of railway enterprises.