Abstract: In order to adapt to the overall planning of CHINA RAILWAY and the development requirements of data centers in multiple-location and multiple-center, and achieve the goal of centralized operation and maintenance management of national railway data centers, this paper proposed a system architecture of multi-location and multi-center monitoring operation and maintenance. Using key technologies such as distributed deployment of monitoring operation and maintenance platform, unified asset management, unified monitoring, etc., the paper implemented the minute-level batch multi-cloud environment patrol and statistical analysis of monitoring data and log data, and put forward optimization suggestions for the use of resources in the cloud environment, with a view to providing important support for the operation and maintenance of the cloud environment in the railway data center.