Abstract: From the perspective of data security management, this paper analyzed the data security requirements in the Classified Protection 2.0 of Cybersecurity series of standards (referred to as Classified Protection 2.0), and combined with the content of data whole lifecycle security governance, put forward the construction scheme and data security protection strategy of the whole life cycle data security technical support system based on the Classified Protection 2.0, which could meet the confidentiality, availability and integrity requirements of data. Improving the data security level according to the requirements of the Classified Protection 2.0 could ensure the security of information systems.