Abstract: In order to promote the sustainable development of China-Europe Railway Express, this paper studied and analyzed the freight price adjustment of China-Europe Railway Express. Combined with the related factors affecting the price of China-Europe Railway Express, including transport costs, supply capacity, market demand, market competition, subsidies and the development trend of foreign trade, the paper proposed the method of system dynamics to solve the problem of China-Europe Railway Express pricing adjustment, established the system dynamics model, and tested the model by taking China-Europe Railway Express (Chengdu) as an example. The simulation results verified the feasibility of the model. The paper proposed a method to adjust the transport price of China-Europe Railway Express under the change of market demand and government subsidies through comparison of various schemes. When the demand factor fluctuated by 4 units, price adjustment range could be within 50 USD/ TEU. To maintain the price advantage and the attractiveness of China-Europe Railway Express cargo sources, government subsidies reduction speed should less than 30%, which means the increased freight prices should within 200～500 USD/TEU. It can provide reference for the direction and scope of freight price adjustment of China-Europe Railway Express.