Abstract: At present, cloud computing has gradually become the mainstream technical architecture of railway information systems, and the process of cloud development of railway data center is accelerating continuously. Meanwhile, railway data center is developing towards multi-location and multi-center direction, with increasingly prominent heterogeneous characteristics of operation and maintenance environment and increasingly complicated operation and maintenance business requirements. To effectively cope with the pressure and challenges facing the operation and maintenance of railway data centers by improving the automatic and intelligent level of the operation and maintenance business of the railway data centers, a solutio to the intelligent operation and maintenance management system of railway data centers is put forward. This paper mainly focuses on operation and maintenance data collection, establishment of index system for the operation and maintenance of railway data centers as well as data storage, laying a solid foundation for the development of the intelligent operation and maintenance management system of railway data centers.