Abstract: Automatic Train Protection On-board Equipment Management Information System（AMIS）is an important embodiment of the intelligent construction of operation and maintenance of electrical service specialty. In order to ensure that the protection of AMIS key data security meets the Classified Protection 2.0 of Cybersecurity, this paper analyzed the data security risks faced in the construction of AMIS, expounded 6 key technologies that help to realize AMIS data security, and put forward the optimization method of AMIS network architecture. Provide theoretical basis for AMIS data security operation and maintenance, and ensure its safe and stable operation